diff --git a/README.md b/README.md
index a411658..10e0bbc 100644
--- a/README.md
+++ b/README.md
@@ -241,6 +241,27 @@ settings:
 1. `matrix.network.read_markers_conditions`
 1. `matrix.network.typing_notice_conditions`
 
+## Cursor bindings
+
+While you can reply on a matrix message using the `/reply-matrix` command (see
+its help in weechat), weechat-matrix also adds a binding in `/cursor` mode to
+easily reply to a particular message. This mode can be triggered either by
+running `/cursor`, or by middle-clicking somewhere on the screen. See weechat's
+help for `/cursor`.
+
+The default binding is:
+
+    /key bindctxt cursor @chat(python.matrix.*):r hsignal:matrix_cursor_reply
+
+This means that you can reply to a message in a Matrix buffer using the middle
+mouse button, then `r`.
+
+This binding is automatically set when the script is loaded and there is no
+such binding yet. If you want to use a different key than `r`, you can execute
+the above command with a different key in place of `r`. To use modifier keys
+like control and alt, use alt-k, then your wanted binding key combo, to enter
+weechat's representation of that key combo in the input bar.
+
 ## Navigating room buffers using go.py
 
 If you try to use the `go.py` script to navigate buffers created by
diff --git a/main.py b/main.py
index a3993ad..ba2eb85 100644
--- a/main.py
+++ b/main.py
@@ -65,7 +65,7 @@ from matrix.bar_items import (
 from matrix.buffer import room_buffer_close_cb, room_buffer_input_cb
 # Weechat searches for the registered callbacks in the scope of the main script
 # file, import the callbacks here so weechat can find them.
-from matrix.commands import (hook_commands, hook_page_up,
+from matrix.commands import (hook_commands, hook_key_bindings, hook_page_up,
                              matrix_command_buf_clear_cb, matrix_command_cb,
                              matrix_command_pgup_cb, matrix_invite_command_cb,
                              matrix_join_command_cb, matrix_kick_command_cb,
@@ -74,7 +74,8 @@ from matrix.commands import (hook_commands, hook_page_up,
                              matrix_olm_command_cb, matrix_devices_command_cb,
                              matrix_room_command_cb, matrix_uploads_command_cb,
                              matrix_upload_command_cb, matrix_send_anyways_cb,
-                             matrix_reply_command_cb)
+                             matrix_reply_command_cb,
+                             matrix_cursor_reply_signal_cb)
 from matrix.completion import (init_completion, matrix_command_completion_cb,
                                matrix_debug_completion_cb,
                                matrix_message_completion_cb,
@@ -695,6 +696,7 @@ if __name__ == "__main__":
         G.CONFIG.read()
 
         hook_commands()
+        hook_key_bindings()
         init_bar_items()
         init_completion()
 
diff --git a/matrix/commands.py b/matrix/commands.py
index 17d9b25..53faf74 100644
--- a/matrix/commands.py
+++ b/matrix/commands.py
@@ -544,6 +544,15 @@ def hook_commands():
         hook_page_up()
 
 
+def hook_key_bindings():
+    W.hook_hsignal("matrix_cursor_reply", "matrix_cursor_reply_signal_cb", "")
+
+    binding = "@chat(python.{}*):r".format(G.BUFFER_NAME_PREFIX)
+    W.key_bind("cursor", {
+        binding: "hsignal:matrix_cursor_reply",
+    })
+
+
 def format_device(device_id, fp_key, display_name):
     fp_key = partition_key(fp_key)
     message = ("    - Device ID:      {device_color}{device_id}{ncolor}\n"
@@ -1930,3 +1939,31 @@ def matrix_send_anyways_cb(data, buffer, args):
         W.prnt("", message)
 
     return W.WEECHAT_RC_ERROR
+
+
+@utf8_decode
+def matrix_cursor_reply_signal_cb(data, signal, ht):
+    tags = ht["_chat_line_tags"].split(",")
+
+    W.command("", "/cursor stop")
+
+    if "matrix_message" in tags:
+        for tag in tags:
+            if tag.startswith("matrix_id_"):
+                matrix_id = tag[10:]
+                break
+        else:
+            return W.WEECHAT_RC_OK
+
+        buffer_name = ht["_buffer_full_name"]
+        bufptr = W.buffer_search("==", buffer_name)
+
+        current_input = W.buffer_get_string(bufptr, "input")
+        input_pos = W.buffer_get_integer(bufptr, "input_pos")
+
+        new_prefix = "/reply-matrix {} ".format(matrix_id)
+
+        W.buffer_set(bufptr, "input", new_prefix + current_input)
+        W.buffer_set(bufptr, "input_pos", str(len(new_prefix) + input_pos))
+
+    return W.WEECHAT_RC_OK